I may have made progress on the original picture. This ancestry.com picture can be included in this message thanks to Google
It is supposed to be Minerva Ann Kirk. It looks like she is the same woman as the one in the portrait. If so, then the couple are James A. (Jim Andy?) Honaker and Minerva or Menerva Ann Kirk Honaker.
Can You Trace Your Line To Robert Lilly ? Yes. He and Fanny are in my family tree more than once.
I was recently informed that the couple in this portrait were Jonathan and Elizabeth Smith Kester, parents of John Mack Kester. Mack was step-father to the children of Oliver Lloyd Lilly, husband of Flossie McComas.