| Subject: |
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B cell activation |
| Name: |
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Taylor |
| Date Posted: |
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Sep 10, 05 - 4:14 AM |
| Email: |
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Allietaylor81@aol.com |
| Message: |
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I have a specific question concerning activation of B cells. When a B cell first encounters an antigen, is there initially clonal expansion, or does there need to be an interaction with T cell to stimulate clonal expansion ? I ask this because, in the primary response, IgM is secreted, and this is prior to class switching...so I assume prior to T cell/B cell interaction. So...
1. does IgM secretion occur before class switching ?
2. if it does, is there any hypermutation ?
3. can IgM cells become memory cells? |
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